Background: The prognostic value of platelet count in chronic heart failure (CHF) is not clearly established. The present study aimed to assesse the independent prognostic value of platelet count in patients with CHF.Methods: From Januay 2016 to December 2019, 1162 patients with a discharge diagnosis of CHF were recorded in present study. The patients were divided into two groups according to the platelet count: low platelet count (LP, ≦140,000/μl) and high plate count (HP, >140,000/μl). The

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... n outcomes were defined as all-cause death or cardiogenic rehospitalization within 3 years. Survival analysis and Cox proportional hazard models adjusted by an established risk score were performed. Results: During 3 years follow-up, the overall main outcomes including all-cause death (P=0.0475) and composite endpoint events of all-cause death or cardiogenic rehospitalization (P=0.0053) were higher in LP group than in those with HP group. After adjusting for other covariables, including gender, age, et al., low platelet count was related to increased the risk of main outcomes during 3 years follow-up (all-cause death, HR:1.151, 95%CI: 1.082-1.670, P=0.040; composite endpoint events, HR: 1.313, 95%CI: 1.152-1.964, P=0.016). Conclusions: Low platelet count was associated with risk for higher adverse outcome in patients with CHF.