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N-terminal sequence-based prediction of subcellular location
Different compartments in a cell perform diverse tasks, thus knowledge of the localization of a protein would be highly indicative of its function. Many proteins have an Nterminal sequence of approximately 20-50 residues, which is responsible for their targeting to the appropriate location and is cleaved off, after the protein has been inserted into the organelle. Such information can be used in computational methods predicting protein localization. There are several methods for prediction ofdoi:10.1186/1471-2105-6-s3-s11 fatcat:b36u75havvg2vn335esjvwj344