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In this article we describe methods for using oxygen-15 water (H 2 O 15 ) positron emmission tomography (PET) to explore the functional neuroanatomy of cognition in awake, non-human primates. The discussion is based on a recent study designed to identify regions in the monkey brain associated with perceiving auditory stimuli, and species-specific calls, in particular . Details are provided concerning critical aspects of the experimental paradigm, including pre-scanning habituation sessionsdoi:10.1016/j.ymeth.2005.08.003 pmid:16466931 pmcid:PMC1550778 fatcat:ihkolf47lvghdgursh74d3m27i