Dendrophen, a Novel Glycyrrhetyl Amino Acid from Dendronephthya hemprichi

Mohamed Shaaban, Khaled A. Shaaban, Howaida I. Abd-Alla, Atef G. Hanna, Hartmut Laatsch
2011 Zeitschrift für Naturforschung. B, A journal of chemical sciences  
Chemical investigation of the extract of Dendronephthya hemprichi, collected from the Red Sea, Egypt, delivered dendrophen (1), the first 3β -acetoxy-glycyrrhetyl amino acid conjugate obtained from nature. Additionally, a new polyhydroxy sterol, dendrotriol (2), together with cholesterol and hexitol were isolated. Chromatographic separation of the low-polarity components of the D. hemprichi extract afforded 4-oxo-pentanoic acid, 2-methyl-acrylic acid 2-diethylaminoethyl ester (3), juniper
more » ... r (4), and 2-octadecanone. The structures of 1 and 2 were confirmed by 1D and 2D NMR studies and mass spectrometry.
doi:10.1515/znb-2011-0413 fatcat:5gnfa4lxrzcmho7i27yta7i47e