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Original Article Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality
Int J Mol Epidemiol Genet
Candidate pathway approaches in disease association studies often utilize a tagSNP approach to capture genetic variation. In this paper we assess gene expression patterns with SNPs in genes in the CHIEF pathway to help determine their potential functionality. Methods: Quantitative real-time RT-PCR was run to determine gene expression of 13 genes in normal colon tissue samples from 82 individuals. TagSNP genotype data were obtained from a GoldenGate Illumina multiplex bead array platform. Age,fatcat:mcwjwmbrsjbdjfoprf5yj2eovu