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Lack of Dramatic Enrichment of Fetal DNA in Maternal Plasma by Formaldehyde Treatment
2005
Clinical Chemistry
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able variations in detection sensitivity and quantification of fetal DNA concentrations were noted among laboratories very familiar with real-time PCR technology (21 ) . Further studies will be needed to clarify this issue in addition to the continued exploration of other strategies for the investigation of complex fetal genetic traits by analysis of maternal plasma. These strategies may include the enrichment of fetal sequences by size-fractionation of plasma DNA (22, 23 ) or the use of mass
doi:10.1373/clinchem.2004.042168
pmid:15738522
fatcat:awfwnfku3vf5bg5jfeh6cqjzbq