This research deals with the dynamic model and control of the distillation tower by applying a multi-loop control system in Matlab/Simulink for a dual mixture of benzene and toluene. The method of control in this research is PID multi -loop. The results showed a good performance of the benzene-toluene system using a single-ended temperature control structures with using bottom and top flow rate controlling bottom and top level respectively based on the calculation of the absolute error integration (IAE).