Autologous Bone Marrow Transplantation in Children with Leukemia Lymphoma Syndrome
自家骨髄移植を施行したleukemia lymphoma syndromeの4例

Yuji FUJII, Koichi HIRANO, Takashi MATSUSHITA, Hiroaki NAKAJIMA, Shuhei YAJIMA, Akira ENDOH, Teruaki HONGO, Yoshio IGARASHI, Takaharu YAMAMOTO, Katsumi YAMADA
1992 The Japanese Journal of Pediatric Hematology  
Five children with leukemia lymphoma syndrome (LLS) in complete remission (CR) were received high-dose chemotherapy and/or total body irradiation followed by autologous bone marrow transplantation (ABMT). Autologous bone marrow was harvested at 1st CR in all patients and purged with 4-hydroperoxycyclophosphamide (4HC) . Although one patient autografted in 2nd CR died of relapse, the other three patients in 1st CR are alive without relapse at +22m , +20m, + 11m. Especially, the treatment in two
more » ... f them was finished within nine months from their diagnosis . Adverse effects of ABMT were a few and tolerable by the supportive cares . ABMT purged with 4HC would be effective and useful treatment in children with LLS .
doi:10.11412/jjph1987.6.408 fatcat:gfdchuak5vghxharib675bewbu