Introduction Inflammation is the primary response of the body against an infection or an injury and it is very essential when it comes to our immunity. It is important to understand about the anti-inflammatory drugs that are available in the market due to the growing prominence of pain and pain-related conditions. This study deals with the anti-inflammatory activity of silver nanoparticles which are synthesized using Solanum Xanthocarpum fruit extract. Materials and Methods 25 grams of dried

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... it powder of Solanum Xanthocarpum was mixed with 250 ml of water..25 ml of plant filtrate was added into 225 ml of aqueous solution of 1mM silver nitrate for reduction of silver nitrate into Ag+ ions and kept at room temperature for 24 hours in a rotating shaker at 28 degree C.After preparation of the silver nanoparticles using Solanum Xanthocarpum fruit extract the anti-inflammatory activity was assessed. Results This research provokes the inflammatory action of silver nanoparticles produced from the plant extracts. It is shown that Solanum Xanthocarpum induced with Silver nanoparticles has a significant inhibitory activity. Conclusion The silver nanoparticles synthesized using the fruit extract Solanum Xanthocarpum showed excellent anti-inflammatory activity.