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CHDOCK: a hierarchical docking approach for modeling Cn symmetric homo-oligomeric complexes
Protein-protein interactions are crucial in many biological processes. Therefore, determining the complex structure between proteins is valuable for understanding the molecular mechanism and developing drugs. Many proteins like ion channels are formed by symmetric homo-oligomers. In this study, we have proposed a hierarchical docking algorithm to predict the structure of C n symmetric protein complexes, which is referred to as CHDOCK. The symmetric binding modes were first constructed by andoi:10.1007/s41048-019-0088-0 fatcat:4zs3ikj33vazpprapzt7iwdgbe