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Theranostics - An Old Concept in New Clothing [Working Title]
Aptamers are a short polymer of oligonucleotides (natural or modified) that can bind to its cognate target (small molecules to large macromolecules like proteins, cells, microorganisms etc.) with high affinity and selectivity. They can fold into unique secondary and tertiary conformation in solution (pH, ionic concentration) and bind to their targets in a specific manner (binding constants in sub-nano to pico molar range). They rival the monoclonal antibodies and other specific biologicaldoi:10.5772/intechopen.95403 fatcat:7s3kto6dzrfjhb7tppquers5mm