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Clinical Trials of Treatment for Hepatitis C Virus Infection in HIV-Infected Patients: Past, Present, and Future
Clinical Infectious Diseases
Coinfection with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) type 1 is common. Rates of liver-related morbidity and mortality have been increasing in the coinfected population, and treatment for HCV infection in this group remains a challenge. The HCV-monoinfected population, especially patients infected with HCV genotype 2 or 3, has benefited dramatically from the advent of treatment with pegylated interferon plus ribavirin; rates of sustained virological response approachdoi:10.1086/429498 pmid:16265616 fatcat:rhtde4cu5va3vewzhqffbrgioe