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Binding of pathogen to host often involves glycans on host epithelial surfaces, a complex process that poses challenges for in vitro studies. In this thesis, methods were developed to study the binding of bacteria to human epithelial membrane glycoproteins by Pseudomonas aeruginosa, a common respiratory pathogen of individuals with cystic fibrosis (CF). A plate assay was developed and revealed differences between the adhesion of clinical strains isolated from four CF patient sputum samples, anddoi:10.25949/19436225 fatcat:5wmr5zorh5adfk2tbgkm3eopxa