Marker-assisted selection of dairy cows for β-casein gene A2 variant

Carla Sebastiani, Chiara Arcangeli, Martina Torricelli, Marcella Ciullo, Nicoletta D'avino, Giulia Cinti, Stefano Fisichella, Massimo Biagetti
2022 Italian Journal of Food Science  
Many studies highlighted potential associations of β-casein A1 with specific human diseases and a minor digestibility of milk, due to the bioactive peptide β-casomorphin 7 (BCM-7) release during digestion. Conversely, the ancestral β-casein A2 variant seems to be a favorable trait because it is not associated with BMC-7 release. The aim of this work was to evaluate frequencies of β-casein variants in offspring of previously genotyped cows inseminated with A2 homozygous semen. The frequency of
more » ... e A2/A2 animals has almost doubled from 37 to 69%. These are encouraging results with the perspective of reaching the goal of producing A2 milk.
doi:10.15586/ijfs.v34i2.2178 fatcat:gl6h2uh4wnckbi3fw3ftui3xve