Adult Large Cell/Anaplastic Medulloblastoma with Myogenic Differentiation: Case Report with Molecular Analysis

Simin Laiq, David G Munoz, Jaragh M, Ginsberg H
2020 American Journal of Medical Case Reports  
Medulloblastoma with myogenic differentiation (MMD), previously termed medullomyoblastoma, is a distinctive subtype of medulloblastoma. It is an uncommon neoplasm in children and very rare in adults, with oldest reported case being 49-years of age. We present a case of large cell/anaplastic medulloblastoma with myogenic differentiation arising in the right cerebellar hemisphere of a 54-year-old man treated by surgical resection and radiotherapy. Despite C-MYC amplification in the tumor, he
more » ... ved tumor-free for nearly 2 years (726 days), which greatly exceeded the expected total survival. His death was attributed to complications of treatment rather than recurrence.
doi:10.12691/ajmcr-9-1-18 fatcat:jw5eigxcgjhoday5isagpp4r7u