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How to Target Spinal Metastasis in Experimental Research: An Overview of Currently Used Experimental Mouse Models and Future Prospects
2021
International Journal of Molecular Sciences
The spine is one of the organs that is most affected by metastasis in cancer patients. Since the control of primary tumor is continuously improving, treatment of metastases is becoming one of the major challenges to prevent cancer-related death. Due to the anatomical proximity to the spinal cord, local spread of metastasis can directly cause neurological deficits, severely limiting the patient's quality of life. To investigate the underlying mechanisms and to develop new therapies, preclinical
doi:10.3390/ijms22115420
pmid:34063821
fatcat:pjm3uder5ngc7ortny4wpzryce