Influence of Intrinsic and Lifestyle Factors on the Development of IgE Sensitization

Teresa Stemeseder, Eva Klinglmayr, Stephanie Moser, Roland Lang, Martin Himly, Gertie J. Oostingh, Joerg Zumbach, Arne C. Bathke, Thomas Hawranek, Gabriele Gadermaier
2017 International Archives of Allergy and Immunology  
versely correlated with IgE levels to PR-10 allergens, and predominately paternal allergies were a predictive factor for IgE sensitization in the children. Vaccination, breastfeeding, and delivery mode showed no influence, while a highly protective effect was observed for growing up on a farm. Of all of the investigated lifestyle factors, only smoking significantly influenced the risk for IgE development. Participants with moderate frequencies of colds showed increased sensitization levels.
more » ... lusion: A hereditary predisposition and lifestyle factors such as a farming environment, smoking, family size, body weight, or frequency of colds significantly influenced the development of allergen-specific IgE in this cohort of adolescents.
doi:10.1159/000475499 pmid:28654924 fatcat:wpk65alyw5a4lnngms4pw44kta