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Hemodynamics of a hydrodynamic injection
2014
Molecular Therapy: Methods & Clinical Development
The hemodynamics during a hydrodynamic injection were evaluated using cone beam computed tomography (CBCT) and fluoroscopic imaging. The impacts of hydrodynamic (5 seconds) and slow (60 seconds) injections into the tail veins of mice were compared using 9% body weight of a phase-contrast medium. Hydrodynamically injected solution traveled to the heart and drew back to the hepatic veins (HV), which led to liver expansion and a trace amount of spillover into the portal vein (PV). The liver
doi:10.1038/mtm.2014.29
pmid:26015971
pmcid:PMC4362352
fatcat:bdwcf2gguzfcxjvntacubkonb4