Severe Weight Loss and Dropped Head Syndrome in MuSK Myasthenia Gravis

Daniel Yu Bing Tan, Willem Hendrik Joseph Peter Linssen, Boris Liberov
2014 Case Reports in Clinical Medicine  
Muscle Specific Receptor Thyrosine Kinase (MuSK) Myasthenia Gravis (MG) is a rare auto-immune disorder of the neuromuscular junction. The clinical presentation of MG is dominated by fluctuat- ing weakness of the extra-ocular, orofacial and limb muscles. The clinical presentation of MuSK MG can vary, which may delay diagnostic procedures. We present a patient who initially presented with severe weight loss and slowly progressive developing neck extensor weakness and diplopia. A single fiber EMG
more » ... ed to the diagnosis MG and antibodies directed towards MuSK were detected. He was treated with prednisone and the steroid sparing agent azathioprine after which he made full recovery.
doi:10.4236/crcm.2014.311127 fatcat:xv44ug7bwna7pk2p3p47uaztuq