Study The Effect of Iraqi Butter Ghee on Some Biochemical Parameters and Histopathological Changes on Aorta of Albino Male Mice. ‫على‬ ‫العزاقية‬ ‫الحيىانية‬ ‫الذهىن‬ ‫على‬ ‫التغذية‬ ‫تأثيز‬ ‫دراسة‬ ‫الكيمىحيىية‬ ‫المعبييز‬ ‫بعض‬ ‫لذكىر‬ ‫االبهز‬ ‫الشزيبن‬ ‫في‬ ‫المزضية‬ ‫النسجية‬ ‫والتغييزات‬ ‫فئزان‬ ‫المهق‬

Jasem Hannon, Hashim Al-Awadi, Merza Hamza
2016 Journal of Kerbala University   unpublished
This study designed to investigate the effects of Iraqi animal oils on aortal tissue as well as biochemical changes of lipid profiles of mice, which feeds, by these oils for six months, the result showed: There were different degrees of significant increase (p<0.05), (p<0.005), (p<0.0005)in TC,TG,LDL,VLDL , and AI, but there was high significant decrease(p<0.0005) in HDL in mice fed on Iraqi animal oils for six months if compared with control group, The histological sections of aorta were
more » ... of aorta were revealed presence of severe histopathological changes, which represented by increase the thickness (89.7±21.3µm) of atherosclerotic plaque in intima which formed by accumulation of lipid droplets (cholesterol, oxidized-LDL), as well as increase the thickness and fibrosis of medial layer. The most severe changes were in aorta, showing significant atherosclerosis and marked luminal narrowing which appeared as semi blocked of blood stream of the aorta of some animals as well as fibrosis and thickness of some areas in some very severe cases. ‫حْبٗه‬ ‫حبرٞش‬ ‫دساست‬ ‫ىغشض‬ ‫اىعَو‬ ‫ٕزا‬ ٌَ‫ص‬ ‫اىَعبٝٞش‬ ‫بعط‬ ٚ‫عي‬ ‫اىعشاقٞت‬ ‫اىحٞ٘اّٞت‬ ُٕ٘‫اىذ‬ ٍِ ‫اىعبىٞت‬ ‫اىْسبت‬ ‫راث‬ ‫اىغزاء‬ ‫بعذ‬ ‫اىَٖق‬ ُ‫اىفئشا‬ ‫رم٘س‬ ٍِ ِٞ‫ٍجَ٘عخ‬ ٚ‫عي‬ ‫االبٖش‬ ُ‫اىششٝب‬ ٜ‫ف‬ ‫اىَشظٞت‬ ‫اىْسجٞت‬ ‫ٗاىخغٞٞشاث‬ ً‫اىذ‬ ُٕ٘‫ىذ‬ ‫اىنَٞ٘حٞ٘ٝت‬ ٜ‫عبى‬ ‫غزاء‬ ٚ‫عي‬ ‫بخغزٝخٖب‬ ‫ٗرىل‬ ‫اىخجشبت‬ ‫حٞ٘اّبث‬ ٜ‫ف‬ ِٕ‫اىذ‬ ‫فشغ‬ ‫حبىت‬ ‫ح٘ىٞذ‬ ‫اسخحزبد‬ ّٜ‫اىحٞ٘ا‬ ‫االصو‬ ‫راث‬ ‫اىعشاقٞت‬ ُٕ٘‫اىذ‬ ‫ىَذة‬ ‫أشٖش‬ ‫سخت‬ ، :ٜ‫ٍبٝي‬ ‫اىذساست‬ ‫ّخبئج‬ ‫اٗظحج‬ ‫ٗقذ‬ ‫ٍعبٍو‬ ‫ٗمزىل‬ ‫جذا‬ ‫اىنزبفت‬ ‫ٗٗاغئت‬ ‫اىنزبفت‬ ‫ٗاغئت‬ ‫اىبشٗحْٞٞت‬ ُٕ٘‫اىزالرٞت,اىذ‬ ‫اىن٘ىٞسخٞشٗه,اىنيٞسٞشٝذاث‬ ٍِ ‫مو‬ ‫اسحفع‬ ‫اىَعْ٘ٝت‬ ‫دسجبث‬ ‫ٗبَخخيف‬ ِٞٝ‫اىششا‬ ‫حصيب‬ ,(p<0.005), (p<0.05) (P<0.0005 ٜ‫عبى‬ ْٛ٘‫ٍع‬ ‫اّخفبض‬ ‫ْٕبك‬ ُ‫مب‬ ‫فَٞب‬) (‫جذا‬ P<0.0005 ‫ٍب‬ ‫ارا‬ ‫اشٖش‬ ‫سخت‬ ‫ىَذة‬ ُٕ٘‫اىذ‬ ٜ‫عبى‬ ‫غزاء‬ ‫حْبٗىج‬ ٜ‫اىخ‬ ُ‫اىفئشا‬ ٜ‫ف‬ ‫اىنزبفت‬ ‫عبىٞت‬ ‫اىبشٗحْٞٞت‬ ُٕ٘‫اىذ‬ ٜ‫ف‬). ِٕ‫اىذ‬ ‫اعخٞبدٝت‬ ُ‫اىفئشا‬ ٜ‫ف‬ ,‫اىسبىبت‬ ‫اىسٞطشة‬ ‫بَجَ٘عت‬ ٓ‫اعال‬ ٓ‫اىَزم٘س‬ ‫اىَخغٞشاث‬ ‫ق٘سّج‬ ‫اىَقب‬ ‫اٗظحج‬ ‫ٍشظٞت‬ ‫حغٞشاث‬ ‫حذٗد‬ ٚ‫اى‬ ‫ىالبٖش‬ ‫اىْسجٞت‬ ‫غع‬-‫ٗعذٝذة‬ ‫شذٝذة‬ ‫ّسجٞت‬ ‫اىذْٕٞت‬ ‫اىطبقت‬ ‫سَل‬ ‫بزٝبدة‬ ‫حَزيج‬ (‫اىَخصيبت‬ (89.7±21.3µm ‫اىنزبفت‬ ‫ٗاغئت‬ ‫اىبشٗحْٞٞت‬ ُٕ٘‫ٗاىذ‬ ‫ببىن٘ىسخٞشه‬ ‫ٗاىََزيت‬ ‫اىذْٕٞت‬ ‫اىقطشاث‬ ٌ‫حشام‬ ‫ّخٞجت‬ ‫اىَخنّ٘ت‬ .)‫ٍخصيبت(سغ٘ة‬ ‫دْٕٞت‬ ‫غبقت‬ ٚ‫اى‬ ‫ٗحح٘ىٖب‬ ‫اىَؤمسذة‬ ‫امز‬ ُ‫مب‬ ‫حٞذ‬ ُٕ٘‫اىذ‬ ‫ٍفشغت‬ ُ‫اىفئشا‬ ‫البٖش‬ ‫اىْسجٞت‬ ‫اىَقبغع‬ ٜ‫ف‬ ‫حذة‬ ‫شٕب‬ ‫ٗجذ‬ ٚ‫اى‬ ‫أدث‬ ٜ‫ٗاىخ‬ ‫سغ٘ة‬ ‫غبقت‬ ‫بشنو‬ ‫اىَخشسبت‬ ‫اىذْٕٞت‬ ‫اىطبقت‬ ‫احسبع‬ ‫بسبب‬ ‫مبٞشة‬ ‫بذسجت‬ ‫االبٖش‬ ُ‫ششٝب‬ ‫حج٘ٝف‬ ‫حعٞق‬ ‫اّسذاد‬ ‫ٍخ‬ ‫ٗبذسجبث‬ ‫حيٞف‬ ‫ٗج٘د‬ ‫ى٘حظ‬ ‫,مَب‬ ‫اىحٞ٘اّبث‬ ‫ىبعط‬ ‫جذا‬ ‫اىحبدة‬ ‫اىحبالث‬ ٜ‫ف‬ ً‫اىذ‬ ٙ‫ىَجش‬ ‫مبٍو‬ ٔ‫شب‬ ‫االبٖش‬ ُ‫اىششٝب‬ ‫ىبعط‬ ‫خيت‬ .ُ‫اىفئشا‬ ‫ىبعط‬ ِٕ‫اىذ‬ ,ِٞٝ‫اىششا‬ ‫حصيب‬ :‫اىبحذ‬ ‫ٍفخبح‬ ‫اىحٞ٘ا‬ ّ ‫,االبٖش‬ ٜ
fatcat:b2knhvwlvnafboc236v2ga5ebm