Evaluation of Antimicrobial and Antifungal potential of (Z)-7-methoxy-1, 5-dihydrobenzo[c] oxepine, isolated from Curcuma caesia Roxb

Arghya Ghosh, Parthadeb Ghosh, Padma Chatterjee, Padma Chatterjee, Arghya Ghosh, Parthadeb Ghosh, Padma Chatterjee
2013 Journal of Scientific and Innovative Research   unpublished
The assessment of antimicrobial potentiality of (Z)-7-methoxy-1, 5-dihydrobenzo[c] oxepine was the primary objective of this study. Assessment of its antimicrobial activity was performed using agar cup method and disc diffusion assay respectively. The bioactive compound was terpenoid in nature. The MIC values tested against different plant pathogenic fungi and bacteria. Antifungal assay showed the MIC values as 22 mg/ ml, 27 mg/ml, and 17 mg/ml for the test fungi Botrytis cinerea, Fusarium
more » ... erea, Fusarium oxysporum and Rhizopus oryzae respectively. The MIC values of this mono-terpenoid was 267 µg/ml, 291 µg/ml, 345 µg/ml, and 467 µg/ml tested against the bacterium Serratia marcescens, Erwinia herbicola, Xanthomonas sp. and Arthrobacter chlorophenolicus respectively. This is the first report of the bioactive nature of (Z)-7-methoxy-1, 5-dihydrobenzo[c]oxepine. Due to its antimicrobial property it may function in plant defense or as an ecofriendly crop protectant or in ethnomedicinal purpose.
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