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Aberrant NDRG1 methylation associated with its decreased expression and clinicopathological significance in breast cancer
2013
Journal of Biomedical Science
Cancer cell differentiation is an important characteristic of malignant tumor and has a great impact on prognosis and therapeutic decision for patients. The N-myc downstream regulated gene 1 (NDRG1), a putative tumor suppression gene, is involved in the regulation of human cell differentiation and metastasis in various cancers. Changes in the status of methylation of the NDRG1 gene have not been studied in detail in human breast cancer. Results: The MDA-MB-231 breast tumor cell line could
doi:10.1186/1423-0127-20-52
pmid:23899187
pmcid:PMC3751627
fatcat:s3xe42imq5ewtlrn4ba2cxevoa