A descriptive study of the prevalence of hypothyroidism among antenatal women and foetal outcome in treated hypothyroid women

Divya Prasad, Neelima Nair, Deepika K.
2016 International Journal of Reproduction Contraception Obstetrics and Gynecology  
The objective of the study was to find out the prevalence of hypothyroidism among pregnant women and to study the foetal outcome in antenatal mothers in whom treatment was initiated early in pregnancy. Methods: This was a descriptive study conducted in the department of OBG Sree Gokulam Medical College, Venjaramoodu, Trivandrum from April 2013 to Oct 2014. 500 antenatal women coming for routine antenatal check up in the first trimester to antenatal OP were screened for
more » ... stimulating hormone) was done in the first trimester and the prevalence of hypothyroidism was estimated. Patients were diagnosed as having subclinical or overt hypothyroidism based on the FT3 (free T3) and FT4 (free T4) results. Patients detected with hypothyroidism -both subclinical and overt were started on appropriate dose of L-thyroxin depending on her gestational age, body weight and level of TSH. Every 6weeks TSH levels were estimated and the dose of the drug adjusted. All these patients were followed up for their foetal outcome such as intrauterine demise, hyperbilirubinemia, prematurity, stillbirths and neonatal hypothyroidism. Results: In the present study, the prevalence of hypothyroidism was 5.6% of which 4% were having subclinical and 1.6% was having overt hypothyroidism. No significant difference in foetal complications, perinatal mortality and morbidity was noted between hypothyroid and euthyroid women. Conclusions: TSH testing should be included in routine antenatal investigations for early detection of subclinical and overt hypothyroidism among antenatal women and early treatment should be initiated so as to prevent complications.
doi:10.18203/2320-1770.ijrcog20161685 fatcat:vne3noofnndh5l7pkfbf5kzile