Industrial control systems (ICS) are facing increasing cybersecurity issues, leading to enormous threats and risks to numerous industrial infrastructures. In order to resist such threats and risks, it is particularly important to scientifically construct security strategies before an attack occurs. The characteristics of evolutionary algorithms are very suitable for finding optimal strategies. However, the more common evolutionary algorithms currently used have relatively large limitations in

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... nvergence accuracy and convergence speed, such as PSO, DE, GA, etc. Therefore, this paper proposes a hybrid strategy differential evolution algorithm based on reinforcement learning and opposition-based learning to construct the optimal security strategy. It greatly improved the common problems of evolutionary algorithms. This paper first scans the vulnerabilities of the water distribution system and generates an attack graph. Then, in order to solve the balance problem of cost and benefit, a cost–benefit-based objective function is constructed. Finally, the optimal security strategy set is constructed using the algorithm proposed in this paper. Through experiments, it is found that in the problem of security strategy construction, the algorithm in this paper has obvious advantages in convergence speed and convergence accuracy compared with some other intelligent strategy selection algorithms.