Chemical investigation of the soft coral Sarcophyton sp. collected from the Saudi territorial Red Sea waters, led to isolation of five terpenoidal metabolites (1-5). Three known sesquiterpenoid derivative; guaiacophine (1), guaia-5, 11(12)-dien (2) and calamenene (3), along with two known cembranoidal diterpenes, 2S*,11S*,12R*-isosarcophytoxide (4) and ent-sarcophine (5) were obtained. The structures of the compounds were established based on their NMR, MS, IR and UV spectral data.