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Working memory revived in older adults by synchronizing rhythmic brain circuits
2019
Nature Neuroscience
Understanding normal brain aging and developing methods to maintain or improve cognition in older adults are major goals of fundamental and translational neuroscience. Here we show a core feature of cognitive decline-working-memory deficits-emerges from disconnected local and long-range circuits instantiated by theta-gamma phase-amplitude coupling in temporal cortex and theta phase synchronization across frontotemporal cortex. We developed a noninvasive stimulation procedure for modulating
doi:10.1038/s41593-019-0371-x
pmid:30962628
pmcid:PMC6486414
fatcat:5xyvxttibveopclqlav23noqdm