Synthesis and Biological Activity of Some Novel Phenyl Pyrazoline Derivatives

SHAILESH H SHAH, PANKAJ S PATEL
2012 Chemical Science Transactions  
A new series of 4-(4-hydroxyphenyl)-3-chloro-1-{4-[5-(substituted phenyl)-1-phenyl-4,5dihydro-pyrazol-3-yl]phenyl}azetidin-2-one were synthesized by reacting 3-chloro-1-{4-[3-(substituted-phenyl)prop-2-enoyl]phenyl}-4-(4-hydroxyphenyl)azetidin-2-one (0.01 M) and phenyl hydrazine (0.01 M) in presence of acetic acid (glacial). All these compounds were characterized by means of their IR, 1 H NMR, spectroscopic data and microanalysis. All the synthesized products were evaluated for their
more » ... al activity. All the compounds were tested for their antibacterial and antifungal activities by broth dilution method.
doi:10.7598/cst2012.274 fatcat:kmtmkckzzjbifjcpfhip2oqjo4