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Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs
2010
Nucleic Acids Research
Small nucleolar RNAs (snoRNAs) and microRNAs are two classes of non-protein-coding RNAs with distinct functions in RNA modification or posttranscriptional gene silencing. In this study, we introduce novel insights to RNA-induced gene activity adjustments in human cells by identifying numerous snoRNA-derived molecules with miRNAlike function, including H/ACA box snoRNAs and C/D box snoRNAs. In particular, we demonstrate that several C/D box snoRNAs give rise to gene regulatory RNAs, named
doi:10.1093/nar/gkq776
pmid:20846955
pmcid:PMC3025573
fatcat:uiiuto2anjftrhnainv2imeira