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Introduction: Down Syndrome (DS) is a genetic disorder that causes global delay in development, including motor function, language and cognitive. Physiotherapy is offered from birth in order to stimulate the acquisition of motor skills. Early intervention presents most benefits, as neural plasticity is at its peak in the first months of life. Objective: This study aimed to investigate the profile of physiotherapy intervention for children with DS during their first three years in specializeddoi:10.1590/1980-5918.029.004.ao05 fatcat:bxufon44pvbxzpva3cavkjzpfe