Renin-angiotensin system blockade in the treatment of heart failure and the role of valsartan in this treatment

Burcak Kilickiran Avci, Baris Ikitimur, Bilgehan Karadag, Zeki Ongen
2015 Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology  
Heart failure which occurs due to various causes including primarily coronary artery diseases and hypertension is a syndrome with complex physiopathology and clinic that can impair patients' quality of life or lead to death. However, it is well known that the activation of renin-angiotensin system (RAS) has an important role in the physiopathology of heart failure with reduced ejection fraction. Therefore, suppression of this system for achieving a gain in the treatment of the disease has been
more » ... mong prominent concerns. In this review, the place of RAS suppressive drugs and valsartan, which is an angiotensin receptor blocker, in heart failure will be examined. (Anadolu Kardiyol Derg 2014; 14(Suppl 2): S1-S8)
doi:10.5152/akd.2014.00001 pmid:25604202 fatcat:qxxs3tkgcraynhbxbtnc3nldze