3-Hydroxycineole bioproduction from 1,8-cineole using Gymnopilus spectabilis 7423 under resting cell conditions

Beatriz Vega, Beatriz Reyes, Paula Rodriguez, Wilson Sierra, David Gonzalez, Pilar Menendez
2015 Biocatalysis  
AbstractThis report describes the high yield biotransformation of 1,8-cineole by the strain Gymnopilus spectabilis 7423, a common fungus isolated from the Eucalyptus tree. The biotransformation was conducted under resting cell conditions and different parameters were tested in order to achieve up to 90% bioconversion. Only two regioisomers were detected, and they were identified as 3-α-hydroxy-1,8-cineole and 2-α-hydroxy-1,8- cineole obtained in a 82:8 ratio.
doi:10.1515/boca-2015-0002 fatcat:3ohhlbro5zcxlfzrs42ilew4zm