The Karaviradi Varga is a group of drugs used in various diseases. The Karavira, Dhattura, Langali, Bhringaraj, Arkapushpa, Kakamachi, Moolak, Shigru, Sarshapa, Bhustrina,Tulasi, Jambira, Kutheraa, Sumukha, Asuri drugs are taken and mixed with Takra(Butter milk) and Sauvira(Fermented barley water) liquid and applied on skin relieve Sidhma, Pama, Pitaka, Krimi, Kustha etc skin diseases. The oil is prepared by these drugs and applied on skin helps to relieve skin diseases. The Kandira

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... Rasona, Grinjana, Palandu, Durduma are used in the Kriminashana(Worms infestation). The Kadali, Sindhuvara, Nirgundi, Aparajita, Jantukara, Bharangi, Varahikanda, Mamsarohini, Suryakanta, Nakuli, Gandhanakuli, Vidhara, Raktapadi, Shankhapushpi, Tanduli, Kasamarda these drugs are triturated in goat's urine and used as Nasya as well as Dhooma(Smoking) alleviate Grahadosha, Jwara, Bhuta, Graha, Unmada, Murcha, Mutrakrichra, Lootavisha(Spider poisoning), Kritrima and Jangama Visha effects, Sarpa Visha(Snake poisoning), Scorpion bite. The Ikshu, Kasha, Darbha, Kusha, Shara, Vamsha, Nala, Durva, Shweta, Neela, Rakta Kumuda, Kamala, Kamalabeeja, Kamalanala, Kamalakeshara are used in Raktapitta Vikara(Bleeding diseases). The present work dealt the number of drugs and their pharmacological actions. Keywords: Dhanwantari Nighantu. Karaviradi Varga, Dhanttura, Langali, Bhringaraj, Moolak, Shigru, Sarshapa etc