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Our understanding of biology has been greatly improved through recent developments in mass spectrometry, which is providing detailed information on protein and metabolite composition as well as protein-metabolite interactions. The high sensitivity and resolution of mass spectrometry achieved with liquid or gas chromatography allows for detection and quantification of hundreds to thousands of molecules in a single measurement. Where homogenization-based sample preparation and extraction methodsdoi:10.2144/000113451 pmid:20701590 pmcid:PMC2967016 fatcat:uwhcbsndxbew3j4atxi2ygjgmq