A Case of a Pregnant Woman with IgA Nephropathy Showing Histological Preeclampsia Findings without Hypertension Treated with Steroids: A Case Report and Literature Review

Nagisa Koda, Kei Matsumoto, Yukio Maruyama, Naomi Ishikawa, Nobuo Tsuboi, Tetsuya Kawamura, Takashi Yokoo
2022
A 35-year-old woman pregnant with twins developed nephrotic syndrome (NS) at 33 weeks' gestation, but her blood pressure remained within the normal range throughout gestation and puerperium. At 34 weeks' gestation, she delivered healthy twins via Caesarean section. After delivery, she developed massive proteinuria (21.1 g/day) and severe hypoalbuminemia (1.0 g/dL). A renal biopsy performed 19 days after delivery revealed IgA nephropathy (IgAN) and preeclampsia. She was treated with steroids,
more » ... the NS gradually resolved. This is a rare case of massive gestational proteinuria with IgAN and preeclampsia pathologically that did not meet the clinical criteria for preeclampsia.
doi:10.2169/internalmedicine.9146-21 pmid:36130896 fatcat:nv3ehhmu4ra5vjncvlxkvt4num