Expression of the c-myc protooncogene in human prostatic carcinoma and benign prostatic hyperplasia

W H Fleming, A Hamel, R MacDonald, E Ramsey, N M Pettigrew, B Johnston, J G Dodd, R J Matusik
1986 Cancer Research  
We have examined the level of c-myc transcripts in prostate tissue obtained from patients with both benign prostatic hyperplasia and adenocarcinoma of the prostate. A significantly higher level of c-myc transcripts is observed in patients with adenocarcinoma (P less than 0.05). In addition, a subset of patients with adenocarcinoma had levels of c-myc transcripts 2-fold higher than the mean level for this group. These preliminary results indicate that the investigation of c-myc levels as a
more » ... c levels as a prognostic indicator in prostatic carcinoma is warranted.
pmid:2417706 fatcat:3hff45khxvenjnn7mpb6fojqtm