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Association Between IL-23 and Coronary Arterial Lesions in Children with Kawasaki Disease
The pathogenesis of coronary artery lesions (CALs) in KD patients has been thought of as an unknown stimulus that triggers an inflammatory cascade with activation of the immune system. However, interleukin-23 (IL-23) is supposed as a key cytokine in inflammatory and autoimmunity diseases. The role of IL-23 in the pathogenesis of CALs has not been fully elucidated. This study explored the relationship between the serum IL-23 levels and CALs in patients with KD. We collected blood specimens fromdoi:10.21203/rs.3.rs-955195/v1 fatcat:2424yizgvfamdo6qejdflfrega