This article discusses the single kakenauwe language prefix. Language is found in Buton district, Southeast Sulawesi Province. The method used in this research is a descriptive method. By using this method, the findings in the study are a single prefix in the language kakenauwe bake-, bako-, ci-, dopo-, fe-, fekhi-, fepe-, fo-, ka-, mem, menci-, mentene -, mo-, na-, nae-, ne, no-, noci-, moko-, nomo-, pa-pisi-, poni-, and sa-.