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help define the optimal drug exposure associated with treatment efficacy. The analyses of data from experimental models with different antifungal drug classes have identified distinct pharmacodynamic characteristics. Results from these models have been useful for defining the relationship between antifungal exposures and efficacy. More recently clinical data has become available allowing similar investigation. These results of these studies have been similar to those from experimental modelsdoi:10.1016/j.ijid.2008.05.074 fatcat:plimnmduzzev3n3sxtyz7ny2ou