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Cordycepin. An inhibitor of newly synthesized globin messenger RNA
1978
Journal of Biological Chemistry
The effect of cordycepin (3'-deoxyadenosine) on newly synthesized globin mRNA in cultured mouse fetal liver erythroid cells is investigated. At cordycepin concentrations that do not inhibit amino acid incorporation into acid-precipitable material, the quantity of pulse-labeled (radioactive) globin mRNA nucleotide sequences is reduced by 90%, as compared to adenosine-treated controls. The reduction of radioactivity in globin-specific RNA sequences is greater than the inhibition of total RNA
pmid:305436
fatcat:mrct6nveyvhuvnyakxf2u4slqu