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Photoacoustics can image spreading depolarization deep in gyrencephalic brain
2019
Scientific Reports
Spreading depolarization (SD) is a self-propagating wave of near-complete neuronal depolarization that is abundant in a wide range of neurological conditions, including stroke. SD was only recently documented in humans and is now considered a therapeutic target for brain injury, but the mechanisms related to SD in complex brains are not well understood. While there are numerous approaches to interventional imaging of SD on the exposed brain surface, measuring SD deep in brain is so far only
doi:10.1038/s41598-019-44935-4
pmid:31209253
pmcid:PMC6572820
fatcat:udovffp5mrhkxaa74s2kgga2jm