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Journal of Chemical and Pharmaceutical Research
A simple, precise, accurate and reproducible RP-HPLC method was developed and validated for simultaneous estimation of ramipril and atorvastatin in bulk and combined pharmaceutical formulations. Separation of ramipril and atorvastatin was successfully achieved on an Inertsil ODS C18 column (150mm x 4.6mm x 5 µm). The mobile phase consisted of 0.1% ortho phosphoric acid and methanol (60:40, v/v) at a flow rate of 1.2 ml/min. The detection was performed at 245 nm. The method was validatedfatcat:k4x7acosprahnna45tummewgiy