PRIMARY NONKERATINIZING SQUAMOUS CARCINOMA OF BREAST WITH IPSILATERAL AXILLARY LYMPH NODE METASTASIS: A CASE REPORT
English

Amoolya Bhat, Vijaya C, Geethamani V, Gurappa V Pyatigoudar, Archana C Shetty
2014 Journal of Evolution of Medical and Dental Sciences  
Primary squamous carcinoma is a rare type of metaplastic carcinoma of the breast, incidence being less than 0.1% of all breast carcinomas. The non-keratinizing variant can mimic several rare types of breast carcinomas, prognosis and therapeutic modalities of which are dissimilar. Histopathological examination is gold standard in diagnosing these tumors. Accurate diagnosis employing special stains and immunohistochemistry is mandatory as they are triple negative unlike infiltrating ductal
more » ... ating ductal carcinoma NOS, and have aggressive course, poor prognosis and distinctive treatment modalities. Other unique features include less frequent axillary nodal metastasis and necessity to rule out metastatic squamous carcinomas to the breast from other primary sites in these patients. We present a 60 years old lady with a hard lump in the left breast, with no significant past history. Physical examination was suggestive of carcinoma of breast with axillary lymphadenopathy. Histopathological examination revealed squamous carcinoma of breast positive for p63 and cytokeratin (CK) 5/6. Her chest X-ray, abdominal ultrasonography, oral cavity, laryngobronchoscopy, cystoscopy and cervical Pap smears were unremarkable ruling out the possibility of primary squamous tumor in other common organs.
doi:10.14260/jemds/2014/2445 fatcat:5bj27j3td5ccxazuvy5ox5a4ni