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SYNTHESIS AND EVALUATION OF NOVEL THIAZOLIDINEDIONES FOR ANTI DIABETIC ACTIVITY
unpublished
The aim of our study was to review on synthesis and various pharmacological activities associated with thaizolidinediones. Thaizolidinediones serve as a boon in the antidiabetic therapy by increasing the sensitivity towards insulin. 1, 3-Thiazolidine-2, 4-dione contains basic skeleton of thiazole or thiazolidine. Presence of one carbonyl group in thiazole at 4 th position makes it thiazolidine-4-one which is known for various activities and presence of another carbonyl group at 2 nd position
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