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A single-cell Raman-based platform to identify developmental stages of human pluripotent stem cell-derived neurons
2020
Proceedings of the National Academy of Sciences of the United States of America
Stem cells with the capability to self-renew and differentiate into multiple cell derivatives provide platforms for drug screening and promising treatment options for a wide variety of neural diseases. Nevertheless, clinical applications of stem cells have been hindered partly owing to a lack of standardized techniques to characterize cell molecular profiles noninvasively and comprehensively. Here, we demonstrate that a label-free and noninvasive single-cell Raman microspectroscopy (SCRM)
doi:10.1073/pnas.2001906117
pmid:32694205
fatcat:m2ey3mmd5bhutedgoye5dzwdqm