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Biochimica et Biophysica Acta (BBA) - Enzymology
MicroRNAs are~21-nt long, non-coding RNAs that play critical roles in post-transcriptional gene regulation. Even though a large number of miRNAs have been identified, annotating their functions remains a challenge. We develop a computational, transcriptome-based approach to annotating stress-inducible microRNAs in plants. With this approach, we find that nineteen microRNA genes of eleven microRNA families in Arabidopsis thaliana are up-regulated by cold stress. Our experiments validate thatdoi:10.1016/0005-2744(68)90151-4 fatcat:zyfmy6q4qzasdk6j5wo2tsd6wm