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The functional role of miRNAs in colorectal cancer: insights from a large population-based study
2019
Cancer Biology and Medicine
Identification of causal microRNAs (miRNAs) in colorectal cancer (CRC) is elusive, due to our lack of understanding of how specific miRNAs affect biological pathways and outcomes. An miRNA can regulate many mRNAs and an mRNA can be associated with many miRNAs; appreciation of these complex networks in which miRNAs operate is necessary to transition from identifying dysregulated miRNAs to identifying individual miRNAs or groups of miRNAs that are suitable for therapeutic purposes. The aim of the
doi:10.20892/j.issn.2095-3941.2018.0514
pmid:31516743
pmcid:PMC6713639
fatcat:hyw2vtjrlvgojh2henxfdrnk4u