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PyDamage: automated ancient damage identification and estimation for contigs in ancient DNA de novo assembly
[article]
2021
bioRxiv
pre-print
DNA de novo assembly can be used to reconstruct longer stretches of DNA (contigs), including genes and even genomes, from short DNA sequencing reads. Applying this technique to metagenomic data derived from archaeological remains, such as paleofeces and dental calculus, we can investigate past microbiome functional diversity that may be absent or underrepresented in the modern microbiome gene catalogue. However, compared to modern samples, ancient samples are often burdened with environmental
doi:10.1101/2021.03.24.436838
fatcat:4v6rwt2nsnbqpgwyiotp2i5ba4