Impact of the COVID-19 Pandemic and Associated Lockdown Measures on the Management, Health and Behaviour of the Cystic Fibrosis Population in France During 2020 (MUCONFIN) [post]

Nadia Oubaya, Thibaut Pombet, Celine Delestrain, Natascha Remus, Benoit Douvry, Dominique Grenet, Harriet Corvol, Guillaume Thouvenin, Virginie Prulière-Escabasse, Hakima Mounir, Dominique Argoud, Cédric Fretigne (+8 others)
2022 unpublished
BackgroundMost of the studies on cystic fibrosis (CF) focused on SARS-CoV-2 prevalence and suggested a low incidence of infection in this population We aimed to assess in cystic fibrosis (CF) patients the impact on healthcare access, health, and behaviour of the pandemic and associated lockdown measures implemented in May 2020 in response to the first wave of SARS-CoV-2 infection.MethodsA national questionnaire opened online from May 10th, 2020 to June 11th, 2020 was completed by 751
more » ... , aged 14 years and over. It comprised questions about access to healthcare, anxiety and depression, smoking, alcohol, drug and psychotropic drug consumption, adherence to CF treatment, and constraints. A semi-structured comprehensive interview was performed no later than one month after the end of the lockdown in 15 CF-patients.ResultsThe mean age of the population was 28 [IQR 20-37] years old. More than 75% of in-person consultations scheduled during the lockdown were cancelled and 27% were postponed, but telehealth consultations were proposed and accepted in almost 40% of cases. More than 75% of the scheduled physiotherapy sessions were cancelled and replaced mainly by self-drainage. Annual follow-up clinic visits were consistently postponed whereas required hospitalizations at CF centres for exacerbation were maintained in most cases. While 43% CF-patients had signs of anxiety, 51% presented symptoms of depression, both associated with increased use of psychotic medications and inversely correlated to COVID-19 prevalence. Among the lower and lower middle classes, very little medical information was obtained or requested by the patient, participation to sports or other activities was low, while excessive home confinement and isolation were more frequent. In contrast, in the upper middle and upper classes, individuals solicitated help to their CF centre, had more physical activities, and maintained contact with friends or families.ConclusionThe first lockdown in France had only minimal impact on the management care of CF-patients but was associated with increased symptoms of anxiety and depression, together with behavioural changes that varied with social class
doi:10.21203/ fatcat:4rlhnzhtvrft5atlnntgygyen4