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Ultrasonic-assisted extraction process and method validation for deoxypodophyllotoxin from the roots of Anthriscus sylvestris: Application of response surface methodology and UPLC–PDA–QDa
Deoxypodophyllotoxin (DPT), or anthricin, is a lignan isolated from the roots of Anthriscus sylvestris and is reported to exhibit anti-inflammatory, anti-oxidant, and anti-asthmatic effects. Herein, the conditions for the extraction of DPT from A. sylvestris are optimized using a Box-Behnken design (BBD) method based on response surface methodology (RSM). DPT was detected by ultra-performance liquid chromatography coupled with photodiode array and quadrupole detector (UPLC-PDA-QDa) anddoi:10.1556/1326.2018.00397 fatcat:qcfc25qp7rapphusih4oa4lv5m