Compulsive versifying after treatment of transient epileptic amnesia

Ione O. C. Woollacott, Phillip D. Fletcher, Luke A. Massey, Amirtha Pasupathy, Martin N. Rossor, Diana Caine, Jonathan D. Rohrer, Jason D. Warren
2014 Neurocase  
Compulsive production of verse is an unusual form of hypergraphia that has been reported mainly in patients with right temporal lobe seizures. We present a patient with transient epileptic amnesia and a left temporal seizure focus, who developed isolated compulsive versifying, producing multiple rhyming poems, following seizure cessation induced by lamotrigine. Functional neuroimaging studies in the healthy brain implicate left frontotemporal areas in generating novel verbal output and rhyme,
more » ... ile dysregulation of neocortical and limbic regions occurs in temporal lobe epilepsy. This case complements previous observations of emergence of altered behavior with reduced seizure frequency in patients with temporal lobe epilepsy. Such cases suggest that reduced seizure frequency has the potential not only to stabilize or improve memory function, but also to trigger complex, specific behavioral alterations.
doi:10.1080/13554794.2014.953178 pmid:25157425 pmcid:PMC4487569 fatcat:bjssepmpvrajzdlsrzw7e2vjli